The Royals welcome back Jimmy Kebe and Mikkel Andersen from injury tonight, and Adrian Mariappa will make his Reading debut.
Kebe & Andersen return from knee injuries, while Mariappa will play after his move from Watford earlier this week.
Chris Gunter picked up an injury in training so will not play, while Simon Church and Jem Karacan are also ruled out.
Pavel Pogrebnyak is not yet selected for his first game in a Reading shirt after only three days' training with his new teammates.
In the first half Michail Antonio starts up front, and in the second half Brynjar Gunnarsson plays right back; Jobi McAnuff in central midfield.
Brian McDermott's men take on CDR Quarteirense, kick off 8pm.
First half: Andersen; Cummings, Shorey, Mariappa, Pearce; Guthrie, Leigertwood (c), Kebe, Robson-Kanu; Antonio, Roberts
Second half: Andersen; Gunnarsson, Harte, Gorkss, Morrison; McAnuff (c), Tabb; McCleary, Obita; Hunt, Le Fondre
Follow the game live on our Twitter feed www.twitter.com/readingfc
and there is also live coverage on BBC Radio Berkshire, also available on their website.