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The Royals cruised to victory against a strong Manchester City side at Madejski Stadium on Sunday afternoon.
It was an incredible start from the home side as Ryan Edwards slipped in a cross for Craig Tanner to smash home from 14 yards out with barely a minute on the clock.
Just two minutes later the Royals scored their second. Good play in the midfield led Lawson D'ath to shoot from 25 yards out with City keeper Eirik Johansen helpless to keep out the 20 year old's fizzing strike.
There wasn't too much for the Royals defence to deal with, with City left back Greg Leigh's cross-come-shot the visitors' only real threat of the opening stages - which Andersen did well to backpedal and tip over the bar.
City's first shot on target came 12 minutes before the end of the first half when Lopes released Albert Rusnak to shoot into the far corner but Andersen had it covered. It was only a matter of seconds until City had their second shot on target when a slip up by the Royals in the middle of the park led to Lopes, once again, providing a through ball to Cole where Andersen's leg kept Reading in it.
Chris Cummins' side then grabbed a third just before the half hour mark - in magical fashion.
Dominic Samuel seemed isolated as he mounted a solo counter attack, but somehow wormed past three or four maroon shirts before slotting home a cracking individual effort.
Reading started the second half like they did the first. A free kick after a tangle between Boyata and Samuel on the edge of the box was curled in by D'Ath but Johansen was equal to the strike and palmed it over the crossbar.
Tanner then fired a half chance high into the stand, before the young forward was again involved - working Johansen from distance.
The top flight Champions boasted full internationals and multi million pound youngsters amongst their ranks, but their attacking endeavours were brilliantly dealt with by a resolute Reading defence - with Niall Keown in particular pulling off some admirable blocks.
Former Real Madrid man Jose Poso La Rosa had half an opening in the dying stages, but both he and the lively Denis Suarez were kept at bay - as the u21s picked up their third win in three games.
Reading: Andersen, Arnold, Webb, Keown, Sweeney, Tabb (C), D'Ath, Edwards, Kelly (Partridge), Tanner (Losasso), Samuel
Subs not used: Henly, Amofah, Dickie
City: Johansen, Facey, Leigh, Huws, Plummer, Boyata (booked), Rusnak, Suarez, Cole, Lopes, La Rosa
Subs: Boassert, Lawlor, Marin, Glendon, Evans