Gunter, HRK & Obita startNigel Adkins has made three changes to the side that picked up a narrow win over Charlton Athletic in midweek.
Chris Gunter returns from suspension to replace Stephen Kelly, whilst Jordan Obita and Hal Robson-Kanu also start - with Jobi McAnuff and Pavel Pogrebnyak dropping to the bench.
Former Royal Ian Harte is on the bench for Bournemouth, whilst frontman Lewis Grabban starts after overcoming an injury scare.
Reading: McCarthy, Cummings, Gunter, Gorkss, Pearce, Guthrie (C), Williams, Obita, McCleary, Robson-Kanu, Sharp
Subs: Federici, Kelly, McAnuff, Drenthe, Le Fondre, Blackman, Pogrebnyak