Fresh faces for United
Royals boss Brian McDermott has made six changes from the side that lost to Stoke City last time out.
Adam Le Fondre earns a start against the side he supported as a boy, partnering Noel Hunt up front.
Mikele Leigertwood shakes off a knock to start in central midfield alongside Jem Karacan. \\\\\\\
Manchester United make eight changes from the side which drew at Real Madrid. Javier Hernandez and Danny Welbeck start in attack, Robin van Persie is on the bench but Wayne Rooney is not in the squad.
Manchester United: De Gea, Smalling, Buttner, Jones, Vidic (c); Anderson, Cleverley, Young, Valencia, Hernandez, Welbeck
Subs: Lindegaard, Ferdinand, Carrick, Giggs, Nani, Kagawa, van PersieReading: Federici, Kelly, Shorey, Mariappa, Morrison, Karacan, Leigertwood, McAnuff (C), McCleary, Hunt, Le Fondre
Subs: Andersen, Gunter, Pearce, Carrico, Guthrie, Robson-Kanu, Pogrebnyak