Cooper, Tanner and Mackie all startRoyals boss Nigel Adkins hands out three full debuts at Glanford Park tonight, starting with Jake Cooper, Craig Tanner and Jamie Mackie for the first time.
Cooper makes his first professional start at Scunthorpe tonight in fact, while Mackie is named up front having missed last weekend's trip to his old stomping ground as part of the conditions of his loan from Nottingham Forest.
Mikkel Andersen is named ahead of Alex McCarthy on the Royals bench, while Sean Long, Shane Griffin and Tariqe Fosu are all named amongst the substitutes for the first time this season.
Adkins is without a full eleven of injured first team players - Obita, Hector, Kelly and Ferdinand at the back, Guthrie, Karacan, McCleary, Tshibola and Williams in midfield, Pogrebnyak and Robson-Kanu in attack. And Oliver Norwood misses out tonight as he is cup-tied!
Scunthorpe: Olejnik, Nolan, Addison, Canavan, Williams, Hawkridge, Bishop, McAllister, McSheffrey, Adelakun, Madden.
Subs: Weaver, Dawson, Sparrow, Taylor, Featherstone, Wootton, Llera.
Reading: Federici, Gunter, Cummings, Cooper, Pearce, Akpan, Kuhl, Tanner, Blackman, Cox, Mackie.
Subs: Andersen, Long, Griffin, Fosu, Stacey, Taylor, Edwards.