Four changes for the RoyalsSteve Clarke makes four changes for the Royals' final home match of the season with Alex Pearce, Oliver Norwood, Danny Williams and Hal Robson-Kanu coming back into the side.
Pearce, who will captain the side, replaces Jake Cooper at the heart of defence and will be partner by Michael Hector.
Adam Federici retains his place between the sticks. Chris Gunter and Jordan Obita will occupy their familiar full-back berths.
Williams and Norwood come into midfield, and will play alongside Nathaniel Chalobah, with Garath McCleary playing on one flank and the returning Robson-Kanu being deployed on the other.
Jamie Mackie will lead the line.
Reading: Federici, Gunter, Obita, Pearce (c), Hector, Norwood, Williams, Chalobah, McCleary, Robson-Kanu, Mackie.
Subs: Andersen, Cooper, Akpan, Karacan, Stacey, Blackman, Cox.
Brentford: Button, Bidwell, Dean, Douglas (c), Odubajo, Judge, Gray, Diagouraga, Pritchard, Jota, Tarkowski.
Subs: Craig, McCormack, Dallas, Bonham, Toral, Smith, O'Connell.