Norwood and Blackman startSteve Clarke has made two changes to the side that won at Wolverhampton Wanderers this past weekend.
Ahead of a hectic February fixture schedule, Oliver Norwood and Nick Blackman step in to replace Hal Robson-Kanu and Simon Cox.
Absent through injury are Danny Guthrie, Chris Gunter, Jem Karacan and Anton Ferdinand.
For Leeds United, former Royals Stuart Taylor and Billy Sharp are both named on the bench.
Reading: Federici, Kelly, Obita, Hector, Pearce (c), Chalobah, Williams, Norwood, Blackman, McCleary, Pogrebnyak
Subs: Andersen, Cooper, Akpan, Robson-Kanu, Mackie, Yakubu, Cox
Leeds: Silvestri, Wootton, Bamba, Bellusci, C Taylor, Byram, Murphy, Cook, Bianchi, Mowatt, Morison.
Subs: S Taylor, Del Fabro, Doukara, Sloth, Antenucci, Cani, Sharp.