Royals boss Jaap Stam has brought the same squad to Sunderland that was named on the teamsheet ahead of our 3-0 win over Barnsley at the Madejski in midweek, and he starts with the same eleven for the third successive game.
Kermorgant starts his third game this week, while Mannone is named between the posts to play against his former employers.
Welshmen Chris Gunter and Dave Edwards start against their former international manager, Chris Coleman, who is in charge of the Black Cats at the Stadium of Light for the first time this afternoon.
Still on the sidelines for the Royals are Garath McCleary, John Swift, Callum Harriott, Stephen Quinn, Joe Mendes, George Evans and Sam Smith.
Former Royals loanee Lewis Grabban is named amongst Sunderland's starters - he last represented the Royals in the play-off final at Wembley back in May.
And the hosts had to make a late change to their line-up after Paddy McNair suffered an injury in the warm-up, so Darren Gibson started in his place and Brendan Galloway came onto the bench for the Black Cats.
Sunderland: Ruiter, Matthews, O'Shea (c), Browning, Oviedo, Cattermole, Honeyman, Gibson, McManaman, McGeady, Grabban.
Subs: Steele, Love , Gibson, Asoro, Gooch, Maja, Wilson.
Reading: Mannone, Bacuna, Gunter, McShane (c), Moore, Van den Berg, Edwards, Kelly, Aluko, Barrow, Kermorgant.
Subs: Jaakkola, Blackett, Ilori, Clement, Beerens, Popa, Bodvarsson.