Anssi Jaakkola starts in goal for the Royals against Bolton Wanderers for the first time in the league this season, as Vito Mannone is absent for personal reasons.
Young striker Danny Loader, fresh from winning the U17 World Cup with England, is in the squad in the league for the very first time as he takes a place on the bench.
Tyler Blackett returns to the starting line-up, as does Dave Edwards, who came on in the first half on Saturday against Wolves, with Joey van den Berg suspended.
Liam Kelly also returns following injury, and he is available from the bench as the Royals make four changes from the weekend's match.
Reading: Jaakkola, Gunter, McShane (c), Moore, Blackett, Bacuna, Edwards, Swift, Barrow, Beerens, Aluko.
Subs: Legg, Ilori, Clement, Bodvarsson, Kelly, Richards, Loader.