Jón Daði Böðvarsson, Liam Kelly, Omar Richards and John Swift all return to the starting line-up for the Royals on Saturday afternoon.
In the case of Böðvarsson and Richards, they both return from injury to take their place in the starting line-up against Preston North End.
Tyler Blackett is absent through injury, while Yann Kermorgant returns from suspension to be among the substitutes at Madejski Stadium.
Tom Holmes has stayed in the first-team squad as well, with the 18-year-old available from the bench in RG2.
Reading: Mannone, Gunter (c), Moore, Ilori, Richards, Bacuna, Kelly, Swift, Barrow, Aluko, Böðvarsson.
Subs: Jaakkola, Van den Berg, Evans, Kermorgant, Clement, Martin, Holmes.
Preston North End: Rudd, Fisher, Huntington, Davies, Cunningham (c), Pearson, Browne, Robinson, Barkhuizen, Bodin, Moult.
Subs: Maxwell, Clarke, Harrop, Maguire, Gallagher, Horgan, Earl.