Paul Clement has made three changes to the side that took on Bolton Wanderers at the weekend, with Blackburn Rovers the opponents on Wednesday night.
Sone Aluko has recovered from a knock to be involved from the start, while Leandro Bacuna and Jón Daði Böðvarsson also get the nod from the start.
Mo Barrow is back from injury, fit enough for a place on the bench as he looks to take on his former club at Ewood Park.
New loan signing, Josh Sims could make his Royals debut on the night, and is available as a substitute in Blackburn.
Paul McShane and Liam Moore continue at centre-back, with Tiago Ilori absent from the 18 on Wednesday and John O'Shea available from the bench.
Reading: Mannone, Yiadom, McShane (c), Moore, Blackett, Bacuna, Kelly, Méïte, Aluko, Baldock, Böðvarsson.
Subs: Walker, O'Shea, Meyler, Swift, Barrow, Sims, McNulty.
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