New Royals boss Paul Clement has named his starting eleven for his first game in the hotseat and Chris Martin starts up front for the Royals this evening.
Martin had been missing through illness before the international break but returns to the squad to lead the line.
Joey van den Berg is restored to the eleven, while Vito Mannone takes his position between the posts once more as Anssi Jaakkola drops to the bench.
John Swift starts for the first time in more than two months - hamstring issues meant he was last in the starting eleven for a goalless draw at Hull in mid-January.
Reading: Mannone, Gunter (c), Ilori, Moore, Blackett, Van den Berg, Edwards, Swift, Aluko, Barrow, Martin.
Subs: Jaakkola, Holmes, Bacuna, Evans, Clement, Smith, Kermorgant.
QPR: Smithes, Furlong, Bidwell, Onuoha, Lynch, Freeman, Cousins, Washington, Scowen, Wszolek, Smith.
Subs: Ingram, Manning, Smith, Robinson, Luongo, Eze, Sylla.