Danny Loader will be making his very first senior start as the Royals take on promotion-chasing Leeds at Elland Road on Tuesday night.
The young striker came off the bench at the weekend for his senior debut, but is given the chance to impress from the beginning as Marcelo Bielsa's Leeds await the Royals this evening.
Tiago Ilori returns to the starting line-up in central defence, making his 50th start in a Reading shirt. Leandro Bacuna comes back into midfield and Andy Yiadom comes into the defence in place of Tyler Blackett in four changes from Saturday's draw against Wigan.
Anssi Jaakkola continues between the posts, with Andy Rinomhota starting his fourth consecutive match in midfield, alongside John Swift and Liam Kelly.
Leeds United: Peacock-Farrell, Douglas, Forshaw, Cooper, Alioski, Roofe, Dallas, Hernandez, Phillips, Baker, Klich.
Subs: Huffer, Roberts, Saiz, Harrison, Shackleton, Clarke, Halme.
Reading: Jaakkola, Gunter, Yiadom, Moore (c), Ilori, Bacuna, Rinomhota, Swift, Kelly, Méïté, Loader.
Subs: Walker, O'Shea, McCleary, Aluko, Sims, Blackett, McNulty.