Paul Clement has made four changes to his Royals side that drew against Ipswich prior to the international break.
Sone Aluko, John Swift, Garath McCleary and Chris Gunter all start for the Royals, with Anssi Jaakkola retaining his place in goal.
Top scorer for our U23s this season, Danny Loader, starts on the bench for the Royals at Wigan this afternoon.
Yakou Méïté leads the line up front, with Andy Rinomhota, Liam Kelly and Swift patrolling the midfield.
Reading: Jaakkola, Gunter, Blackett, Moore (c), O'Shea, Rinomhota, Kelly, Swift, McCleary, Aluko, Méïté.
Subs: Walker, Yiadom, Bacuna, Sims, Ilori, McNulty, Loader.