Reading have made three changes to their starting line-up, following their midweek encounter against Leeds United.
Midfield duo, Ovie Ejaria and John Swift are missing from the squad through illness and injury respectively, with Pelé and Garath McCleary coming in to replace them in Reading's midfield.
The defence sees Andy Yiadom return in place of Chris Gunter following his one-match suspension, and George Pușcaș and Yakou Méïté continue to lead the line for the Royals.
On the bench, Charlie Adam returns from a knock and Lucas João makes the matchday squad, having completed an hour on his return from injury with our Under-23s on Thursday afternoon.
Wigan Athletic: Marshall, Sterling, Robinson, Morsy (c), Mulgrew, Dunkley, Pilkington, Macleod, Jacobs, Windass, Garner.
Subs: Jones, Kipre, Massey, Naismith, Lowe, Gelhardt, K Moore.
Reading: Rafael, Yiadom, Miazga, Moore (c), Morrison, Richards, Rinomhota, Pelé, McCleary, Méïté, Pușcaș.
Subs: Walker, Gunter, Loader, Boyé, Blackett, Adam, João.