The 3-0 home defeat to Brentford on Tuesday night has prompted Royals boss Mark Bowen to make five changes to the side that starts at Kenilworth Road this afternoon.
Three of the back four have been switched, with Tom McIntyre and Gabe Osho coming in for Chris Gunter and Liam Moore - while Tyler Blackett starts on the left side in place of Jordan Obita.
Rinomhota, Ejaria and Swift keep their places in midfield - the latter taking the captain's armband for the first time as a Royal.
George Puscas returns to lead the line, while Michael Olise drops to the bench with Sam Baldock to allow Pele to start. Lucas Boye and Omar Richards are both named as a substitute.
Luton Town: Sluga, Potts, Tunnicliffe, Bradley (c), Pearson, Lee, Cornick, Ruddock-Mpanzu, Carter-Vickers, Collins, Brown.
Subs: Cranie, McManaman, Berry, Hylton, Shinnie, Moncur, Bree, Butterfield, Shea.
Reading: Rafael, Osho, Blackett, McIntyre, Morrison, Pele, Rinomhota, Swift (c), Ejaria, Meite, Puscas.
Subs: Walker, Richards, Gunter, Moore, Masika, Boye, Olise, McCleary, Baldock.