Royals boss Veljko Paunović has made three changes to the side that beat Wycombe in midweek at the Madejski - with Tomás Esteves and Alfa Semedo both handed their full debuts for the club.
Esteves starts in place of the absent Tom Holmes, while Semedo is called into the eleven as Michael Olise drops to the bench.
The other change comes up front as the matchwinner in midweek, Lucas João , makes way for George Pușcaș. João is available off the substitutes bench.
Moore ended the Wycombe win with a hobble, but he continues alongside Morrison at the back following the team's fifth clean sheet in six league games.
Reading: Rafael, Esteves, Richards, Moore, Morrison, Rinomhota, Laurent, Semedo, Ejaria, Méïté, Pușcaș.
Subs: Southwood, Gibson, McIntyre, Tetek, Olise, Aluko, João.
Rotherham: Blackman, Mattock, MacDonald, Wood, Wiles, Lindsay, Harding, Ihiekwe, Smith, Barlaser, Jozefzoon.
Subs: Johansson, Jones, Hirst, Lapado, Sadlier, Olosunde, Crooks.
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